Tuesday, October 22, 2013

5 Best Biotech Stocks For 2014

The GuruFocus special feature 52-week low Value Screen is a great research tool to help investors quickly sort through the 740 USA stocks currently listed at a 52-week low, not to mention thousands of other stocks around the world.

Today�� focus is on stocks that are a little more than 50% off high in a 52-week low, along with company financial updates from the second quarter of 2013.

Investor billionaires are holding some of these stocks:

Dendreon Corp. (DNDN)

The current DNDN share price is $3.39, or 53% off the 52-week high of $7.22.

Down 27% over 12 months, Dendreon Corp. (DNDN) has a market cap of $534.26 million, and trades at a P/S of 1.63.

Dendreon is a biotechnology company focused on the discovery, development and commercialization of novel therapeutics that improve cancer treatment options for patients. Its product portfolio includes active cellular immunotherapy and small molecule product candidates.

Revenue and net income tracking:

5 Best Biotech Stocks For 2014: Neoprobe Corporation(NEOP)

Neoprobe Corporation, a biomedical company, engages in the development and commercialization of precision diagnostics that enhance patient care and improve patient benefit. The company is developing and commercializing targeted agents aimed at the identification of occult (undetected) disease. Neoprobe?s two lead radiopharmaceutical agent platforms, Lymphoseek and RIGScan are intended to help surgeons better identify and treat certain types of cancer. Lymphoseek is a diagnostic imaging agent intended for radiolabeling and administration in radiodetection and visualization of the lymphatic system draining the region of injection for delineation of the lymphatic tissue; and RIGScan is an intraoperative biologic targeting agent consisting of a radiolabeled murine monoclonal antibody. The company has a biopharmaceutical development and supply agreement with Laureate Biopharmaceutical Services, Inc. to support the initial evaluation of the viability of the CC49 master working c ell bank, as well as the initial steps in re-validating the commercial production process for the biologic agent used in RIGScan CR. The company was founded in 1983 and is based in Dublin, Ohio.

5 Best Biotech Stocks For 2014: Sanofi(SNY)

sanofi-aventis engages in the discovery, development, and distribution of therapeutic solutions to improve the lives of everyone. The company offers a range of healthcare assets, including a broad-based product portfolio in prescription drugs, OTC/OTX, generics, vaccines, and animal health. It has a strategic alliance with Regulus Therapeutics Inc. to discover, develop, and commercialize micro-RNA therapeutics, initially in fibrosis. The company was founded in 1970 and is headquartered in Paris, France.

Advisors' Opinion:
  • [By Stephen Simpson, CFA]

    If there's a downside to Lexicon's partnering opportunities, it's that there aren't many obvious partners left. Unless one of the existing companies in the SGLT space chose to abandon an existing partnership, Novo Nordisk, Roche (RHHBY.OB), and Takeda may be the best candidates to partner with Lexicon, and that's the sort of limited pool that can lead to hard bargaining. Sanofi (SNY) may also belong in this pool as well, though. While the company did reach a licensing agreement with Chugai for an SGLT2 inhibitor in Japan, that agreement was limited in scope and the drug does not appear on Sanofi's August 2013 pipeline chart.

  • [By Brian Orelli]

    There are a few reasons doctors haven't flocked to prescribe Qsymia in large numbers:

    One bitten, twice shy. It's not particularly surprising that doctors might be a little tentative about prescribing an obesity drug, considering how previous obesity drugs have fared. Wyeth's fen-phen, Abbott Labs' (NYSE: ABT  ) Meridia, and Sanofi's (NYSE: SNY  ) Acomplia were all pulled off the shelves after side effects were discovered. Meridia's heart issues were uncovered in a post-marketing clinical trial. Acomplia never made it to market in the U.S., and European regulators pulled it off the market after real-world usage showed less efficacy and more-common psychiatric side effects.

    It costs what? There are probably some patients not taking the drug simply because of the cost. Only one third of patients with insurance have coverage for Qsymia, and many of those are at the Tier 3 level, where copays are higher, typically $50 to $100. VIVUS is shooting for having 50% coverage of people on private insurance by end of the year, which should help with sticker shock, as have the free trials and discount drugs for those not covered by insurance.

    Not for sale (here). When Qsymia launched last year, the Food and Drug Administration limited its sales to mail-order pharmacies. While it's arguably more convenient to get drugs delivered to your doorstep, ordering through a mail-order pharmacy requires more initial effort than purchasing drugs at a local pharmacy. Fortunately last month, the FDA told VIVUS it could start selling Qsymia in retail pharmacies, which will begin by mid-July.

    VIVUS has spent lots of money jumping over hurdles to make the drug more appealing to patients. And it plans to spend more launching a direct-to-consumer print and digital media campaign. With any luck, VIVUS will be able to find a partner to help pay for the investment. It certainly isn't cheap, and there aren't any guarantees of making it back.

Hot Oil Stocks To Own Right Now: Incyte Corporation(INCY)

Incyte Corporation focuses on the discovery and development of proprietary small molecule drugs for hematologic and oncology indications, and inflammatory and autoimmune diseases. Its product pipe line includes INCB18424, which is in Phase III clinical trial for myelofibrosis; Phase III trial for polycythemia vera; Phase III trial for essential thrombocythemia; Phase I/II trial to treat solid tumors/other hematologic malignancies; and Phase IIb trail for the treatment of psoriasis. The company?s portfolio also includes INCB28050, a Phase IIb clinical trial product for rheumatoid arthritis; INCB28060, a Phase I/II product for solid tumors; INCB7839, a Phase II product for breast cancer; and INCB24360, a Phase I/II product for solid tumors. It has a collaborative research and license agreements with Novartis International Pharmaceutical Ltd.; Eli Lilly and Company; and Pfizer Inc. The company was founded in 1991 and is headquartered in Wilmington, Delaware.

Advisors' Opinion:
  • [By Paul Ausick]

    Big earnings winners: Incyte Corp. (NASDAQ: INCY) up 34.4% to $36.02 on a successful drug trial, Target Corp. (NYSE: TGT) down 3.5% to $65.54 on weak earnings and lowered outlook, and Lowe�� Companies Inc. (NYSE: LOW ) up 4.4% at $46.01 on strong earnings and an improved outlook.

  • [By Maxx Chatsko]

    The best part about being a buy-and-hold investor is that when volatility strikes and analysts and pundits are panicking, you can calmly go about your business and steal great companies at bargain prices. One of the stocks on my top watchlist is Incyte (NASDAQ: INCY  ) , which is a growing biotech company focused on developing oncology and anti-inflammatory drugs. The company's shares have recently fallen below $20 for the first time since early February, which I think warrants a deeper look. In the following video, I'll break down the pros and cons of adding Incyte to your portfolio, although I think the company has a lot of potential in its pipeline.

  • [By John McCamant]

    Incyte's (INCY) crackerjack medicinal chemistry team continues to show that they can create better and differentiated drug candidates from the competition.

    The key near-term driver for INCY is Jakafi growth, and with the increased sales guidance, the company is delivering. The drug's overall profile continues to improve and the recent survival data proves that Jakafi does much more for myelofibrosis patients than just control symptoms.

5 Best Biotech Stocks For 2014: Dendreon Corporation(DNDN)

Dendreon Corporation, a biotechnology company, engages in the discovery, development, and commercialization of therapeutics to enhance cancer treatment options for patients. The company offers active cellular immunotherapy and small molecule product candidates to treat various cancers. Its product candidates comprise Provenge (sipuleucel-T), an active cellular immunotherapy for the treatment of metastatic, castrate-resistant prostate cancer; DN24-02, an investigational active immunotherapy for the treatment of patients with bladder, breast, ovarian, and other solid tumors expressing HER2/neu; and TRPM8, a small molecule agonist to transient receptor potential ion channel, for multiple cancers. The company also has a range of products in preclinical studies, which include Carcinoembryonic antigen for the treatment of lung, colon, and breast cancer; and Carbonic AnhydraseIX for the treatment of kidney cancer. Dendreon Corporation was founded in 1992 and is headquartered in S eattle, Washington.

Advisors' Opinion:
  • [By Dan Caplinger]

    On Thursday, Dendreon (NASDAQ: DNDN  ) will release its latest quarterly results. The key to making smart investment decisions on stocks reporting earnings is to anticipate how they'll do before they announce results, leaving you fully prepared to respond quickly to whatever inevitable surprises arise. That way, you'll be less likely to make an uninformed kneejerk reaction to news that turns out to be exactly the wrong move.

  • [By Sean Williams]

    This week's winner
    Although there was no company-specific news out of�Dendreon (NASDAQ: DNDN  ) this week, following weeks of poor performance, it tacked on 8.7%. Presentations at the American Society of Clinical Oncology's annual meeting two weeks ago certainly helped to excite investors with regard to the potential of immunotherapy stocks, but Dendreon needs a lot more help than what a few early and mid-stage studies can offer. If Dendreon is to keep this rally going, it'll need decisively positive data on advanced prostate cancer treatment Provenge in Europe. We should certainly know more about its progress in Europe within the next few months.

  • [By David Hanson]

    8. Dendreon (NASDAQ: DNDN  ) Many investors consider biotech investing too volatile and too risky. If you have followed Dendreon's stock performance over the last five years, you probably wouldn't argue with that notion. The company does not have a huge basket of drugs to bolster earnings while developing new home-run products. As the company continues to burn through cash and be weighed down by debt, the threat of shareholder dilution will keep many major investors, including Buffett, far away from the stock.

  • [By Rich Smith]

    This series, brought to you by Yahoo! Finance, looks at which upgrades and downgrades make sense, and which ones investors should act on. Today, our headlines include a new buy rating for Workday (NYSE: WDAY  ) , a higher price target for Raytheon (NYSE: RTN  ) , and a lower one for Dendreon (NASDAQ: DNDN  ) . Let's dive right in.

5 Best Biotech Stocks For 2014: Fuse Science Inc (DROP.PK)

Fuse Science, Inc. ( Fuse Science), incorporated on September 21, 1988, is a consumer products holding company. The Company maintains the rights to sublingual and transdermal delivery systems for bioactive agents that can effectively encapsulate and charge many varying molecules in order to produce complete product formulations which can be consumed orally, applied topically or delivered otherwise sublingually or transdermally, thereby bypassing the gastrointestinal tract and entering the blood stream directly. The Fuse Science technology is designed to accelerate conveyance of medicines or nutrients relative to traditional pills and liquids and can enhance how consumers receive these products. In December 2012, the Company launched its initial DROP products, PowerFuse, an energy formulation in a concentrated drop and ElectroFuse, an electrolyte formula in a concentrated drop, online, with the expansion into targeted retail distribution channels.

The Compan y is developing formulations and devices, which are compatible with alternative delivery systems for energy, medicines, vitamins and minerals, among other bioactives. These alternative systems include, but are not limited to, sublingual, transdermal and buccal drug delivery methods. use Science has developed and continues to advance, in conjunction with its scientific team, sublingual and transdermal delivery systems for bioactives that can effectively encapsulate and charge varying molecules in order to produce product formulations which can be consumed orally, applied topically or otherwise delivered sublingually or transdermally, thereby bypassing the gastrointestinal tract and entering the blood stream directly. The delivery technology is consists of encapsulation vesicles and ion exchange permeation enhancers. This technology utilizes a gradient across the mucosa membrane to help deliver the bioactive more efficiently through the mucosa.

The Company

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